Venkata R. Duvvuri

Areas of Expertise

• data science and machine learning
• genomic epidemiology
• public health microbiology
• one health approach
• health administrative and Electronic Health Record (EHR) data

Appointments

Assistant Professor, Laboratory Medicine and Pathobiology, University of Toronto

Academic Degrees and Accreditations

• Postgraduate program in Artificial Intelligence and Machine Learning: Business Analytics, McCombs School of Business, The University of Texas at Austin
• Master of Public Health, School of Public Health and Health Systems, University of Waterloo
• Master of Science (Biology), Faculty of Science, York University
• Doctor of Philosophy (Zoology), Osmania University

PHO Research Interests

• Incorporate data science and machine learning into public health microbiology and genomics to develop risk discovery, assessment and prediction models
• Develop combined genomic and epidemiological methods and approaches to study pathogen transmission and epidemic dynamics
• Identify genomic biomarkers from pathogen genomes to develop novel and rapid molecular diagnostic tests and vaccine candidates using immunoinformatics
• Accelerate public health surveillance and planning by integrating public health and healthcare strategies

PHO Research Activities

• Develop a genome-based machine learning model to address challenges of antimicrobial resistance (AMR) in public health
• Examine the evolutionary and transmission dynamics of viral (for example COVID-19, Respiratory syncytial virus (RSV)), bacterial and fungal pathogens using phylodynamics
• Collaborate on the development of novel and rapid diagnostics for infectious diseases using immunoinformatics
• Provide expertise in data science protocols and machine learning approaches

Selected Publications

1. Lee JW, Su Y, Baloni P, Chen D, Pavlovitch-Bedzyk AJ, Yuan D, Duvvuri VR, et al. Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19. Nat Biotechnol. 2022;40(1):110-20.
2. Su Y, Chen D, Yuan D, Lausted C, Choi J, Dai CL, Voillet V, Duvvuri VR, et al. Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19. Cell. 2020;183(6):1479-95.e20.
3. Hicks JT, Lee D-H, Duvvuri VR, Kim Torchetti M, Swayne DE, Bahl J. Agricultural and geographic factors shaped the North American 2015 highly pathogenic avian influenza H5N2 outbreak. PLoS Pathog. 2020;16(1):e1007857.
4. Duvvuri VR, Deng X, Teatero S, Memari N, Athey T, Fittipaldi N, et al. Population structure and drug resistance patterns of emerging non-PCV-13 Streptococcus pneumoniae serotypes 22F, 15A, and 8 isolated from adults in Ontario, Canada. Infect Genet Evol. 2016;42:1-8.
5. Duvvuri VR, Granados A, Rosenfeld P, Bahl J, Eshaghi A, Gubbay JB. Genetic diversity and evolutionary insights of respiratory syncytial virus A ON1 genotype: global and local transmission dynamics. Sci Rep. 2015;5:14268.

View more publications by Venkata R. Duvvuri on PubMed.gov